适合国情的慢性阻塞性肺疾病防诊治 •
代表性研究成果名称 类别 成果为第一完成单位 本室固定人员参加名单 所属研究方向
适合国情的慢性阻塞性肺疾病防诊治
成果佐证清单
序号 成果类型 成果名称 完成人 刊物、出版社或授权单位名称 年、卷、期、页或专利号
1 论文 Lung function and incidence of chronic obstructive pulmonary disease after improved cooking fuels and kitchen ventilation: A 9-year prospective cohort study Zhou Y, Zou Y, Li X, Chen S, Zhao Z, He F, Zou W, Luo Q, Li W, Pan Y, Deng X, Wang X, Qiu R, Liu S, Zheng J, Zhong N, Ran P PLoS Medicine 2014;11(3): e1001621
2 论文 Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial Zheng JP, Wen FQ, Bai CX, Wan HY, Kang J, Chen P, Yao WZ, Ma LJ, Li X, Raiteri L Sardina M, Gao Y, Wang BS, Zhong NS The Lancet Respiratory Medicine 2014 ;2(3):187-194
3 论文 Roflumilast for the treatment of COPD in an Asian population: a randomized, double-blind, parallel-group study Zheng J, Yang J, Zhou X, Zhao L, Hui F, Wang H, Bai C, Chen P, Li H, Kang J,Brose M, Richard F, Goehring UM, Zhong N Chest 2014;145(1):44-52
4 论文 Tanshinone IIA inhibits lipopolysaccharide-induced MUC1 overexpression in alveolar epithelial cells Zhang K, Wang J, Jiang H, Xu X, Wang S, Zhang C, Li Z, Gong X, Lu W American Journal of Physiology-lung Cellular and molecular Physiology 2014;306(1):C59-65
5 论文 Bone morphogenetic protein 4 inhibits liposaccharide-induced inflammation in the airway Li Z, Wang J, Wang Y, Jiang H, Xu X, Zhang C, Li D, Xu C, Zhang K, Qi Y, Gong X, Tang C, Zhong N, Lu W European Journal of Immunology 2014; 44(11):3283-3294
6 论文 Peak expiratory flow as a screening tool to detect airflow obstruction in a primary health care setting Tian J, Zhou Y, Cui J, Wang D, Wang X, Hu G, Tian Y, Jiang Y, Zheng J, Wang J, Zhong N, Ran P. International Journal of Tuberculosis and Lung Disease 2012,16(5):674-680
7 论文 Development and validation of a chronic obstructive pulmonary disease screening questionnaire in China Zhou YM, Chen SY, Tian J, Cui JY, Li XC, Hong W, Zhao ZX, Hu GP, He F, Qiu R, Wang XP, Wang DL, Zheng JP, Zhong NS, Ran PX Journal of Tuberculosis and Lung Disease 2013;17(12):1645-1651
8 论文 Upregulation of gelatinases and epithelial-mesenchymal transition in small airway remodeling associated with chronic exposure to wood smoke Zou Y, Li S, Zou W, Hu G, Zhou Y, Peng G, He F, Li B, Ran P Plos One 2014;9(5):e96708
9 论文 Development  and  systematic oxidative stress of a rat model of chronic bronchitis and emphysema induced by biomass smoke Hu G, Zhou Y, Hong W, Tian J, Hu J, Peng G, Cui J, Li B, Ran P. Experimental Lung Research 2013;39(6):229-240
10 论文 A model as an alternative method of spirometry for primary screening of COPD in Chinese community clinic Cui J, Zhou Y, Wang X, Zheng J, Zhong N, Ran P. Journal Of Thoracic Disease 2012;4(6):594-600
11 论文 Early intervention with tiotropium in Chinese patients with GOLD stages I-II chronic obstructive pulmonary disease (Tie-COPD): study protocol for a multicentre, double-blinded, randomized, controlled trial Li X, Zhou Y, Chen Sh, Zheng J, Zhong N, Ran P. BMJ Open 2014;4(2):e003991
12 论文 Nicotine induced epithelial-mesenchymal transition via Wnt/β-catenin signaling in human airway epithelial cells Zou W, Zou Y, Zhao Z, Li B, Ran P. American Journal of Physiology-Lung Cellular and Molecular Physiology 2013;304(4):L199-209
13 论文 LANTERN: A randomized study of QVA149 versus salmeterol/fluticasone combination in patients with COPD Zhong N,Wang C,Zhou X,Zhang N,Humphries M,Wang L,Thach C,Patalano F,Banerji D, LANTERN Investigators International Journal of Chronic Obstructive Pulmonary Disease 2015; 10:1015-1026
14 论文 Carbocisteine attenuates hydrogen peroxide-induced inflammatory injury in A549 cells via NF-κB and ERK1/2 MAPK pathways Wang W, Zheng JP, Zhu SX , Guan WJ, Chen M, Zhong NS International Immunopharmacology 2015 ;24(2):306-313
15 发明专利 S-( 羧甲基)- 半胱氨酸药物化合物及其制备方法和用途 钟南山,陈矛,朱少璇 ,郑劲平,万平,王玮 莫红缨,廖维,胡海容,余瑜,傅祥麟 冯金,黄冰娥,张琳 中华人民共和国国家知识产权局 专利号201210234440.4 授权公告日 2014.06.25